Pub. Date : 1999 Dec
PMID : 10628896
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Haloperidol is a substrate of CYP3A4 and an inhibitor, as well as a stimulator, of CYP2D6. | Haloperidol | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | Reduced haloperidol is also a substrate of CYP3A4 and inhibitor of CYP2D6. | Haloperidol | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | In vivo pharmacogenetic studies have indicated that the metabolism and disposition of haloperidol may be regulated by genetically determined polymorphic CYP2D6 activity. | Haloperidol | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |