Pub. Date : 2000 Jan 7
PMID : 10625313
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability. | Nitroglycerin | nitric oxide synthase 3 | Rattus norvegicus |
| 2 | It remains to be elucidated, however, whether long-term treatment with NTG alters the activity and expression of the endothelial NO synthase (NOS III) and whether this enzyme can contribute to O(2)(.-) formation. | Nitroglycerin | nitric oxide synthase 3 | Rattus norvegicus |
| 3 | We studied the influence of long-term NTG treatment on the expression of NOS III as assessed by RNase protection assay and Western blot. | Nitroglycerin | nitric oxide synthase 3 | Rattus norvegicus |
| 4 | These findings suggest that NTG treatment increases the expression of a dysfunctional NOS III gene, leading to increased formation of O(2)(.-) and decreased vascular NO bioavailability. | Nitroglycerin | nitric oxide synthase 3 | Rattus norvegicus |