Title : Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model.

Pub. Date : 1999 Oct

PMID : 10616961






1 Functional Relationships(s)
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1 Results indicated that CCl4 significantly increased the elimination half-life (t(1/2)) of antipyrine from 2.59 +/- 1.04 to 11.25 +/- 3.91 h (P < 0.001) and decreased its clearance (CL) from 65.94 to 10.84 ml/h as compared to control. Antipyrine C-C motif chemokine ligand 4 Rattus norvegicus