Title : Interleukin-8 gene repression by clarithromycin is mediated by the activator protein-1 binding site in human bronchial epithelial cells.

Pub. Date : 2000 Jan

PMID : 10615065






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TNF-alpha-induced promoter activity in this segment showed a significant repression by CAM. Clarithromycin tumor necrosis factor Homo sapiens
2 In accord with promoter analyses, an electrophoretic mobility shift assay showed that CAM repressed AP-1 binding in TNF-alpha-treated BET-1A cells; however, TNF-alpha induced both AP-1 and NF-kappaB binding activities in BET-1A cells. Clarithromycin tumor necrosis factor Homo sapiens