Pub. Date : 2000 Jan
PMID : 10607731
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 2 | The modulation of benzo[a]pyrene diolepoxide (BPDE)-DNA adduct levels by polymorphisms in the CYP1A1, GSTM1 and GSTT1 genes was assessed in leukocytes of Caucasian males. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 3 | The modulation of benzo[a]pyrene diolepoxide (BPDE)-DNA adduct levels by polymorphisms in the CYP1A1, GSTM1 and GSTT1 genes was assessed in leukocytes of Caucasian males. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 4 | Higher levels of BPDE-DNA adducts in individuals with the combined CYP1A1(1/*2 or *2A/*2A)-GSTM1*0/*0 genotype suggest that these genotype combinations are at increased risk for contracting lung cancer when exposed to PAH. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |