Title : A novel mechanism for the melatonin inhibition of testosterone secretion by rat Leydig cells: reduction of GnRH-induced increase in cytosolic Ca2+.

Pub. Date : 1999 Dec

PMID : 10601975






2 Functional Relationships(s)
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1 Both ionomycin and thapsigargin potentiated GnRH-induced testosterone secretion; however, ionomycin, but not thapsigargin, partially prevented the inhibitory effect of melatonin on cells stimulated with GnRH. Ionomycin gonadotropin releasing hormone 1 Rattus norvegicus
2 Both ionomycin and thapsigargin potentiated GnRH-induced testosterone secretion; however, ionomycin, but not thapsigargin, partially prevented the inhibitory effect of melatonin on cells stimulated with GnRH. Ionomycin gonadotropin releasing hormone 1 Rattus norvegicus