Pub. Date : 1999 Nov
PMID : 10598025
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dimethylarsinic acid exposure causes accumulation of Hsp72 in cell nuclei and suppresses apoptosis in human alveolar cultured (L-132) cells. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 2 | We previously found that 72-kDa heat shock protein (Hsp72) was induced and accumulated in the nuclei, together with DNA damage, in human alveolar epithelial (L-132) cells by exposure to dimethylarsinic acid (DMAA), which is a main metabolite of inorganic arsenics in mammals. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 3 | We previously found that 72-kDa heat shock protein (Hsp72) was induced and accumulated in the nuclei, together with DNA damage, in human alveolar epithelial (L-132) cells by exposure to dimethylarsinic acid (DMAA), which is a main metabolite of inorganic arsenics in mammals. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 4 | In the present study, the intracellular behavior of Hsp72 was investigated during the recovery from the DNA damage induced by exposure to DMAA. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 5 | The induction of Hsp72 by exposure to DMAA reached a peak at 6-9 h after removal of DMAA. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 6 | The induction of Hsp72 by exposure to DMAA reached a peak at 6-9 h after removal of DMAA. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 7 | However, the cell-nuclear distribution of Hsp72 was observed until 3 h after the start of DMAA-free incubation. | Cacodylic Acid | heat shock protein family A (Hsp70) member 1A | Homo sapiens |