Title : Enhanced cholesterol reduction by simvastatin in diltiazem-treated patients.

Pub. Date : 1999 Oct

PMID : 10583033






1 Functional Relationships(s)
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1 AIMS: To investigate whether an interaction between diltiazem and the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor simvastatin may enhance the cholesterol-lowering response to simvastatin in diltiazem-treated patients. Diltiazem 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens