Title : Expression of an active, monomeric catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase (PDE5).

Pub. Date : 1999 Dec 3

PMID : 10574925






2 Functional Relationships(s)
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1 The catalytic fragment and full-length PDE5 have similar IC(50) values for the inhibitors 3-isobutyl-1-methylxanthine (20 microM) and sildenafil (Viagra(TM))(4 nM). Sildenafil Citrate phosphodiesterase 5A Homo sapiens
2 The catalytic fragment and full-length PDE5 have similar IC(50) values for the inhibitors 3-isobutyl-1-methylxanthine (20 microM) and sildenafil (Viagra(TM))(4 nM). Sildenafil Citrate phosphodiesterase 5A Homo sapiens