Pub. Date : 1999 Nov 15
PMID : 10574795
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The molecular symmetry brings the two bound AMP-PNP molecules, at the centre of two extended surface regions, to a common side of the dimeric hexokinase I molecule. | Adenylyl Imidodiphosphate | hexokinase 1 | Homo sapiens |
2 | CONCLUSIONS: The binding of AMP-PNP to a protein site separated from the catalytic centre of human hexokinase I can be related to the role played by some nucleotides in dissociating the enzyme from the mitochondrial membrane, and helps in defining the molecular regions of hexokinase I that are expected to be in contact with the mitochondrion. | Adenylyl Imidodiphosphate | hexokinase 1 | Homo sapiens |
3 | CONCLUSIONS: The binding of AMP-PNP to a protein site separated from the catalytic centre of human hexokinase I can be related to the role played by some nucleotides in dissociating the enzyme from the mitochondrial membrane, and helps in defining the molecular regions of hexokinase I that are expected to be in contact with the mitochondrion. | Adenylyl Imidodiphosphate | hexokinase 1 | Homo sapiens |