Title : Dependence of NF-kappaB activation and free radical generation on silica-induced TNF-alpha production in macrophages.

Pub. Date : 1999 Oct

PMID : 10569191






1 Functional Relationships(s)
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1 Pretreatment of the cells with catalase (H2O2 scavenger) or deferoxamine (*OH scavenger) effectively inhibits NF-kappaB and TNFalpha activation, whereas superoxide dismutase (O2 scavenger) has an opposite effect. Hydrogen Peroxide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus