Title : Expression and regulation of phospholipase D isoforms in mammalian cell lines.

Pub. Date : 2000 Jan

PMID : 10567919






1 Functional Relationships(s)
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1 In PC12K cells, which express only PLD2, treatment with nerve growth factor causes neurite outgrowth and increases expression of PLD2 mRNA and protein within 6-12 h. A corresponding increase is observed in membrane PLD activity and in phorbol-12-myristate-13-acetate (PMA)-stimulated PLD activity in intact cells. Tetradecanoylphorbol Acetate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens