Title : Resistance to thyroid hormone caused by a new mutation (V336M) in the thyroid hormone receptor beta gene.

Pub. Date : 1999 Oct

PMID : 10560954






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In vitro expression studies showed that this mutant TRbeta has an impaired triiodothyronine (T3)-dependent transactivation that reduces the activity of the wild-type TRbeta (dominant negative effect). Triiodothyronine T cell receptor beta locus Homo sapiens
2 In vitro expression studies showed that this mutant TRbeta has an impaired triiodothyronine (T3)-dependent transactivation that reduces the activity of the wild-type TRbeta (dominant negative effect). Triiodothyronine T cell receptor beta locus Homo sapiens
3 In vitro expression studies showed that this mutant TRbeta has an impaired triiodothyronine (T3)-dependent transactivation that reduces the activity of the wild-type TRbeta (dominant negative effect). Triiodothyronine T cell receptor beta locus Homo sapiens
4 In vitro expression studies showed that this mutant TRbeta has an impaired triiodothyronine (T3)-dependent transactivation that reduces the activity of the wild-type TRbeta (dominant negative effect). Triiodothyronine T cell receptor beta locus Homo sapiens