Title : Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases.

Pub. Date : 1999 Nov 4

PMID : 10556088






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Together with the previous finding that the PI4P5K product phosphatidylinositol 4,5-bisphosphate (PIP(2)) activates ERM proteins in vitro [16], our data suggest that PIP(2), and not ROCK kinases, is involved in the RhoA-dependent activation of ERM proteins in vivo. Phosphatidylinositol 4,5-Diphosphate prolactin induced protein Homo sapiens
2 Together with the previous finding that the PI4P5K product phosphatidylinositol 4,5-bisphosphate (PIP(2)) activates ERM proteins in vitro [16], our data suggest that PIP(2), and not ROCK kinases, is involved in the RhoA-dependent activation of ERM proteins in vivo. Phosphatidylinositol 4,5-Diphosphate prolactin induced protein Homo sapiens