Title : Purine analogues kill resting lymphocytes by p53-dependent and -independent mechanisms.

Pub. Date : 1999 Jun

PMID : 10554810






1 Functional Relationships(s)
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1 To resolve the controversy concerning the role of p53 in the killing of resting lymphocytes by purine nucleoside analogues, we examined the cytotoxic effects of chlorodeoxyadenosine, fludarabine and deoxycoformycin (plus deoxyadenosine) on unstimulated spleen cells from p53-knockout versus wild-type mice. Purine Nucleosides transformation related protein 53, pseudogene Mus musculus