Pub. Date : 1999 Nov 15
PMID : 10553092
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated whether cytokines and the topical glucocorticoid budesonide differentially regulate RANTES, monocyte chemoattractant protein-4 (MCP-4), and eotaxin mRNA and protein expression in the human bronchial epithelial cell line BEAS-2B and in primary human bronchial epithelial cells by Northern blot analysis and ELISAs. | Budesonide | C-C motif chemokine ligand 11 | Homo sapiens |
| 2 | Although budesonide inhibited the expression of chemokine mRNA to a variable extent, it effectively inhibited production of eotaxin and RANTES protein. | Budesonide | C-C motif chemokine ligand 11 | Homo sapiens |
| 3 | Budesonide inhibited both RANTES- and eotaxin promoter-driven reporter gene activity. | Budesonide | C-C motif chemokine ligand 11 | Homo sapiens |
| 4 | Budesonide also selectively accelerated the decay of eotaxin and MCP-4 mRNA. | Budesonide | C-C motif chemokine ligand 11 | Homo sapiens |