Title : Mechanisms of protection afforded by cyclooxygenase inhibitors to endothelial function against ischemic injury in rat isolated hearts.

Pub. Date : 1999 Nov

PMID : 10547094






1 Functional Relationships(s)
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1 Pretreatment with 6-MNA, 30 microM, a COX-2 inhibitor with some activity on COX 1, diclofenac, 1 microM (COX-1 and -2), or 1-(7-carboxyheptyl) imidazole, 10 microM [thromboxane (TX) synthase inhibitor] but not indomethacin, 10 microM (COX-1 inhibitor) preserved the vasodilation induced by 5-HT after ischemia. 6-methoxy-2-naphthylacetic acid cytochrome c oxidase II, mitochondrial Rattus norvegicus