Pub. Date : 1999 Nov 2
PMID : 10544021
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we showed that the topoisomerase II inhibitor of widely used anticancer drugs etoposide and doxorubicin activated wt p53 in BL2, a Burkitt"s lymphoma cell line which overexpressed MDM2. | Etoposide | MDM2 proto-oncogene | Homo sapiens |
| 2 | This p53 was co-immunoprecipitated with MDM2, but p53 activated by etoposide or doxorubicin barely complexed with MDM2. | Etoposide | MDM2 proto-oncogene | Homo sapiens |