Title : Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells.

Pub. Date : 1999 Nov

PMID : 10543746






2 Functional Relationships(s)
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1 On the other hand, FK506, which is also a macrolide derivative, inhibited transcriptional activation of both NF-kappaB and NFAT more strongly than EM did. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens
2 Expression of calcineurin did not render transactivation of NF-kappaB in T cells more resistant to EM, while the inhibitory effect of FK506 on transactivation of NF-kappaB was attenuated. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens