Pub. Date : 1999 Nov
PMID : 10537140
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mitogen-activated protein (MAP) kinases are involved in interleukin-1 (IL-1)-induced IL-6 synthesis in osteoblasts: modulation not of p38 MAP kinase, but of p42/p44 MAP kinase by IL-1-activated protein kinase C. We previously reported that interleukin-1alpha (IL-1alpha)-induced activation of protein kinase C (PKC) via phosphatidylcholine-specific phospholipase C (PC-PLC) limits IL-6 synthesis induced by IL-1alpha itself in osteoblast-like MC3T3-E1 cells. | Phosphatidylcholines | interleukin 6 | Mus musculus |