Pub. Date : 1999
PMID : 10536878
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These data emphasize the hypothesis that ACE inhibitors act with mixed-type inhibition, which is consistent with their slow-tight binding to the ACE active center, also with binding of chloride on a critical lysine residue leading to a potential conformational change, and finally with the fact that ACE has two domains, each bearing one catalytic site. | Chlorides | angiotensin I converting enzyme | Homo sapiens |