Title : hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage.

Pub. Date : 1999 Oct 26

PMID : 10535931






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, treatment of human cells with the S(N)1 DNA methylators N-methyl-N-nitrosourea or N-methyl-N"-nitro-N-nitrosoguanidine results in p53 phosphorylation on serine residues 15 and 392, and these phosphorylation events depend on the presence of functional hMutSalpha and hMutLalpha. Methylnitrosourea tumor protein p53 Homo sapiens