Title : Direct effects of endotoxin on the endothelium: barrier function and injury.

Pub. Date : 1999 Oct

PMID : 10532583






1 Functional Relationships(s)
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1 The lipid A moiety is responsible for LPS-induced activation of the non-CD14-bearing EC, and agents that bind to and neutralize this highly conserved portion of the LPS molecule can crossprotect against EC barrier dysfunction elicited by LPS derived from diverse species of Gram-negative bacteria. Lipid A CD14 molecule Homo sapiens