Title : Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.

Pub. Date : 1999 Oct 19

PMID : 10526205






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This strain expresses recombinant human cytochrome P450 1A2 and NADPH-P450 reductase and carries out the metabolic conversion of aromatic and heterocyclic amines into DNA-reactive mutagens. Amines cytochrome P450 family 1 subfamily A member 2 Homo sapiens