Pub. Date : 1999 Oct 14
PMID : 10523856
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Downstream of protein kinase C (PKC), the effects of TPA are often mediated by the Raf-1/MEK/ERK mitogen-activated protein kinase (MAPK) cascade, and Raf-1 has been implicated in MDR1 induction by serum and mitogens. | Tetradecanoylphorbol Acetate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
| 2 | Downstream of protein kinase C (PKC), the effects of TPA are often mediated by the Raf-1/MEK/ERK mitogen-activated protein kinase (MAPK) cascade, and Raf-1 has been implicated in MDR1 induction by serum and mitogens. | Tetradecanoylphorbol Acetate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
| 3 | TPA also activated the Raf1/MEK/ERK cascade and activated another MAPK member, p38, but not JNK. | Tetradecanoylphorbol Acetate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |