Title : Repaglinide as monotherapy in Type 2 diabetes.

Pub. Date : 1999

PMID : 10522838






3 Functional Relationships(s)
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1 The action of repaglinide, a carbamoylmethyl benzoic acid derivative, mimics the physiological insulin secretion that is deficient in Type 2 diabetes mellitus. repaglinide insulin Homo sapiens
2 Repaglinide stimulates insulin release from beta-cells only in the presence of glucose. repaglinide insulin Homo sapiens
3 In one study, repaglinide (0.25-4.0 mg preprandially) caused a dose-dependent decrease in blood glucose and a non-dose-dependent increase in insulin over 4 weeks (all doses p < 0.001 vs. placebo). repaglinide insulin Homo sapiens