Pub. Date : 1999 Sep 22
PMID : 10521702
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan-induced serine phosphorylation of cPLA2 and eicosanoid production. | Zymosan | phospholipase A2, group IVA (cytosolic, calcium-dependent) | Mus musculus |
| 2 | IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan-induced serine phosphorylation of cPLA2 and eicosanoid production. | Zymosan | phospholipase A2, group IVA (cytosolic, calcium-dependent) | Mus musculus |
| 3 | Conversely, in macrophages stimulated by zymosan, IL-13 added 30 min before zymosan inhibited the AA release and the serine phosphorylation of cPLA2 induced by the phagocytic agonist. | Zymosan | phospholipase A2, group IVA (cytosolic, calcium-dependent) | Mus musculus |