Title : Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.

Pub. Date : 1999 Oct 22

PMID : 10521508






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The ability of coexpressed GRK2 and arrestins to promote internalization of the CXCR4 mutants revealed distinct differences between respective mutants and suggested that the integrity of the dileucine motif (Ile-328 and Leu-329) and serines 324, 325, 338, and 339 are critical for receptor internalization. Isoleucine G protein-coupled receptor kinase 2 Homo sapiens