Title : Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.

Pub. Date : 1999 Nov

PMID : 10520140






1 Functional Relationships(s)
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1 Northern blot analysis demonstrated that the GR mRNA level was significantly increased by 14-day treatment with desipramine (+142% over control), amitriptyline (+108%), mianserin (+124%), paroxetine (+42%) and sulpiride (+92%), but not with haloperidol. Sulpiride nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus