Pub. Date : 1999 Oct
PMID : 10508523
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. | Folic Acid | folate receptor 1 (adult) | Mus musculus |
| 2 | Previous experiments have identified a folate-binding protein (Folbp1) that functions as a membrane receptor to mediate the high-affinity internalization and delivery of folate to the cytoplasm of the cell. | Folic Acid | folate receptor 1 (adult) | Mus musculus |
| 3 | To determine whether Folbp1 is involved in maternal-to-fetal folate transport, we inactivated Folbp1 in mice. | Folic Acid | folate receptor 1 (adult) | Mus musculus |
| 4 | Our results suggest that Folbp1 has a critical role in folate homeostasis during development, and that functional defects in the human homologue (FOLR1) of Folbp1 may contribute to similar defects in humans. | Folic Acid | folate receptor 1 (adult) | Mus musculus |
| 5 | Our results suggest that Folbp1 has a critical role in folate homeostasis during development, and that functional defects in the human homologue (FOLR1) of Folbp1 may contribute to similar defects in humans. | Folic Acid | folate receptor 1 (adult) | Mus musculus |