Title : Morphine tolerance and transcription factor expression in mouse spinal cord tissue.

Pub. Date : 1999 Sep 10

PMID : 10507546






1 Functional Relationships(s)
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1 Western blots demonstrate a 1.9-fold increase in cyclic AMP response element binding protein (CREB) and a 2.4-fold increase phospho-CREB immunoreactivities in spinal cord homogenates from morphine tolerant animals. Morphine cAMP responsive element binding protein 1 Mus musculus