Title : Linking iodine with autoimmune thyroiditis.

Pub. Date : 1999 Oct

PMID : 10502541






3 Functional Relationships(s)
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1 The disease, moreover, can be transferred adoptively, using spleen cells from iodine-fed donors treated in vitro with iodinated thyroglobulin. Iodine thyroglobulin Mus musculus
2 Based on T-cell proliferation, it appears that the NOD-H2(h4) strain of mice has innately a greater response to murine thyroglobulin than do other mouse strains and that the proliferation is increased even more by feeding iodine. Iodine thyroglobulin Mus musculus
3 We suggest, therefore, that the presence of iodine increases the autoantigenic potency of thyroglobulin, a major pathogenic antigen in the induction of autoimmune thyroiditis. Iodine thyroglobulin Mus musculus