Title : The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid.

Pub. Date : 1999 Sep 15

PMID : 10493497






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The cyclooxygenase inhibitor aspirin and the 5-lipoxygenase inhibitor MK-886 both partially inhibited DNA synthesis in response to NNK. MK-886 arachidonate 5-lipoxygenase Homo sapiens