Title : Co-operative binding sites for transported substrates in the multiple drug resistance transporter Mdr1.

Pub. Date : 1999 Oct 1

PMID : 10491158






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Additionally, verapamil increased the Hill coefficient of Mdr1 for progesterone from 1.1 to 3.2. Progesterone ATP binding cassette subfamily B member 1 Homo sapiens
2 These results indicate the existence of multiple binding sites (at least four for progesterone) for transported substrate in Mdr1 and a complicated mode of interactions between them. Progesterone ATP binding cassette subfamily B member 1 Homo sapiens