Title : Comparison of heparin- and dermatan sulfate-mediated catalysis of thrombin inactivation by heparin cofactor II.

Pub. Date : 1999 Sep 24

PMID : 10488098






7 Functional Relationships(s)
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1 Comparison of heparin- and dermatan sulfate-mediated catalysis of thrombin inactivation by heparin cofactor II. Dermatan Sulfate serpin family D member 1 Homo sapiens
2 Heparin and dermatan sulfate activate heparin cofactor II (HCII) comparably, presumably by liberating the amino terminus of HCII to bind to exosite I of thrombin. Dermatan Sulfate serpin family D member 1 Homo sapiens
3 Heparin and dermatan sulfate activate heparin cofactor II (HCII) comparably, presumably by liberating the amino terminus of HCII to bind to exosite I of thrombin. Dermatan Sulfate serpin family D member 1 Homo sapiens
4 Heparin and dermatan sulfate activate heparin cofactor II (HCII) comparably, presumably by liberating the amino terminus of HCII to bind to exosite I of thrombin. Dermatan Sulfate serpin family D member 1 Homo sapiens
5 Fluorescence spectroscopy revealed that dermatan sulfate evokes greater conformational changes in HCII than heparin, suggesting that dermatan sulfate stimulates HCII by producing more effective displacement of the amino terminus. Dermatan Sulfate serpin family D member 1 Homo sapiens
6 Fluorescence spectroscopy revealed that dermatan sulfate evokes greater conformational changes in HCII than heparin, suggesting that dermatan sulfate stimulates HCII by producing more effective displacement of the amino terminus. Dermatan Sulfate serpin family D member 1 Homo sapiens
7 Fluorescence spectroscopy revealed that dermatan sulfate evokes greater conformational changes in HCII than heparin, suggesting that dermatan sulfate stimulates HCII by producing more effective displacement of the amino terminus. Dermatan Sulfate serpin family D member 1 Homo sapiens