Title : [A new cause of resistant arterial hypertension: coprescription with anticonvulsant treatments].

Pub. Date : 1999 Aug

PMID : 10486655






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Following explanation can be hypothesis: several antihypertensive drugs are liver-metabolised by microsomal cytochrome P450 3A4 isoform that could explain a significantly decreased half-life in association with enzymatic inducers, such as rifampicine or antiepileptic drugs (phenobarbital, phenytoin or carbamazepine). Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens