Title : Cyclooxygenase-2 expression and function in the medullary thick ascending limb.

Pub. Date : 1999 Sep

PMID : 10484519






3 Functional Relationships(s)
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1 In the present study, we demonstrated that the COX-2-selective inhibitor, NS-398, prevented tumor necrosis factor-alpha (TNF)- and phorbol myristate acetate (PMA)-mediated increases in PGE(2) production by cultured MTAL cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor necrosis factor Homo sapiens
2 In the present study, we demonstrated that the COX-2-selective inhibitor, NS-398, prevented tumor necrosis factor-alpha (TNF)- and phorbol myristate acetate (PMA)-mediated increases in PGE(2) production by cultured MTAL cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor necrosis factor Homo sapiens
3 The time-dependent inhibition of 86Rb uptake by MTAL cells challenged with TNF was diminished by pretreating cells with NS-398. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor necrosis factor Homo sapiens