Title : Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro.

Pub. Date : 1999 Sep

PMID : 10484461






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that attracts monocytes and has a tyrosine residue critical for function. Tyrosine C-C motif chemokine ligand 2 Homo sapiens
2 Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that attracts monocytes and has a tyrosine residue critical for function. Tyrosine C-C motif chemokine ligand 2 Homo sapiens
3 These findings are consistent with nitration of tyrosine by peroxynitrite, with subsequent inhibition of MCP-1 binding to monocytes, and suggest that peroxynitrite may play a role in regulation of MCP-1-induced monocyte chemotaxis. Tyrosine C-C motif chemokine ligand 2 Homo sapiens