Title : Chronic hypersecretion of luteinizing hormone in transgenic mice selectively alters responsiveness of the alpha-subunit gene to gonadotropin-releasing hormone and estrogens.

Pub. Date : 1999 Sep

PMID : 10478837






1 Functional Relationships(s)
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1 These studies provide in vivo evidence that estrogen-negative feedback on alpha and LHbeta subunit gene expression requires GnRH input, reflecting an indirect mechanism of action of the steroid. Steroids gonadotropin releasing hormone 1 Mus musculus