Title : c-Jun triggers apoptosis in human vascular endothelial cells.

Pub. Date : 1999 Sep 3

PMID : 10473668






2 Functional Relationships(s)
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1 To extend our understanding of the role of c-Jun in EC physiology, we have directed overexpression of c-Jun in human umbilical vein ECs by using a tetracycline-regulated adenoviral expression system. Tetracycline Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Tetracycline can effectively shut off c-Jun overexpression and prevent EC apoptosis. Tetracycline Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens