Pub. Date : 1999 Jun
PMID : 10471061
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Its expression in Saccharomyces cerevisiae enabled us to obtain, at a high level, an active yeast-expressed CYP2B6 protein, so as to assess its role in the metabolism of ethoxyresorufin, pentoxyresorufin, benzyloxyresorufin, ethoxycoumarin, testosterone and cyclophosphamide. | pentoxyresorufin | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Kinetic analysis showed that human CYP2B6 preferentially metabolized benzyloxyresorufin and pentoxyresorufin, although other CYPs also metabolized these substrates in human liver microsomes. | pentoxyresorufin | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |