Title : Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways.

Pub. Date : 1999 Aug

PMID : 10455888






1 Functional Relationships(s)
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1 CONCLUSIONS: Treatment with CPT effectively inhibited the growth of the human gastric cancer SIIA; the mechanism involved was induction of apoptosis mediated by up-regulation of p53, p21Waf1/Cip1, and p27Kip1 and the down-regulation of Bcl-2 and Bcl-XL. Camptothecin tumor protein p53 Homo sapiens