Title : Carbonic anhydrase inhibitors: N-cyanosulfonamides, a new class of high affinity isozyme II and IV inhibitors.

Pub. Date : 1999

PMID : 10445050






1 Functional Relationships(s)
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1 Spectroscopic studies on Co(II)-substituted hCA II proved that the new inhibitors directly bind to the metal ion within the enzyme active site, similarly to the classical inhibitors of the unsubstituted sulfonamide type. Sulfonamides carbonic anhydrase 2 Homo sapiens