Pub. Date : 1999 Jul
PMID : 10443458
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nigericin, a K+/H+ ionophore, which can induce a decrease in pHi, at 2-10 microM in 2 min incubation reduced both platelet aggregation and an increase in cytoplasmic free Ca2+ concentration ([Ca2+]i) stimulated with thrombin or U46619. | Nigericin | prothrombin | Oryctolagus cuniculus |
2 | When pHi was artificially altered during the ranges of 6.6-7.4 by treatment with nigericin in K+-rich medium, aggregation by low concentrations of thrombin was dependent on the pHi. | Nigericin | prothrombin | Oryctolagus cuniculus |