Title : An update on the mechanism of action of the Steroidogenic Acute Regulatory (StAR) protein.

Pub. Date : 1999

PMID : 10433061






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The Steroidogenic Acute Regulatory (StAR) protein has been demonstrated to be an indispensable component in the acute regulation of steroid hormone biosynthesis. Steroids steroidogenic acute regulatory protein Homo sapiens
2 The Steroidogenic Acute Regulatory (StAR) protein has been demonstrated to be an indispensable component in the acute regulation of steroid hormone biosynthesis. Steroids steroidogenic acute regulatory protein Homo sapiens
3 The StAR protein, which is rapidly synthesized in response to tropic hormone stimulation, apparently functions by mediating the transfer of the substrate for all steroid hormones, cholesterol, from the outer to the inner mitochondrial membrane where it is cleaved to pregnenolone, the first steroid formed. Steroids steroidogenic acute regulatory protein Homo sapiens
4 The StAR protein, which is rapidly synthesized in response to tropic hormone stimulation, apparently functions by mediating the transfer of the substrate for all steroid hormones, cholesterol, from the outer to the inner mitochondrial membrane where it is cleaved to pregnenolone, the first steroid formed. Steroids steroidogenic acute regulatory protein Homo sapiens
5 Mutations in the StAR gene have been shown to be the only cause of the potentially fatal disease, lipoid congenital adrenal hyperplasia, in which the affected individual can synthesize virtually no steroids. Steroids steroidogenic acute regulatory protein Homo sapiens