Title : Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation.

Pub. Date : 1999 Aug 2

PMID : 10430626






1 Functional Relationships(s)
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1 Here we demonstrate that Lck and Fyn can be activated by proline motifs in the CD28 and CD2 proteins, respectively. Proline FYN proto-oncogene, Src family tyrosine kinase Homo sapiens