Title : A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate.

Pub. Date : 1999 May 14

PMID : 10421442






1 Functional Relationships(s)
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1 Organophosphates equilibrate with AChE prior to phosphorylating the active site serine residue, and as predicted propidium had little effect on the phosphorylation rate constants for the fluorogenic organophosphate ethylmethyl-phosphonylcoumarin (EMPC). Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens