Title : Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential.

Pub. Date : 1999 Jun 1

PMID : 10418968






1 Functional Relationships(s)
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1 Tranylcypromine and diethyldithiocarbamate were found to be less specific, with inhibitory effects towards several CYP isoforms, including CYP2A6, CYP2C9, CYP2C19, and CYP2E1. Ditiocarb cytochrome P450 family 2 subfamily E member 1 Homo sapiens