Title : In vitro effect of granulocyte-colony stimulating factor and all-trans retinoic acid on the expression of inflammatory cytokines and adhesion molecules in acute promyelocytic leukemic cells.

Pub. Date : 1999 Jul

PMID : 10414449






2 Functional Relationships(s)
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1 Our results have shown that ATRA induces an increased expression of IL-8, IL-1beta, TNF-alpha and ICAM-1 in APL cells, which can be amplified by the addition of G-CSF. Tretinoin colony stimulating factor 3 Homo sapiens
2 Furthermore, G-CSF, through its potent differentiating activity, may increase the risk of such complications during ATRA treatment. Tretinoin colony stimulating factor 3 Homo sapiens