Pub. Date : 1999 Jun
PMID : 10405886
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Indeed, the initial success of systemic IFN-alpha treatment in AIDS-associated Kaposi"s sarcoma (AIDS-KS) occurred before identification of the human immunodeficiency virus (HIV) and in the absence of any coherent view of KS pathogenesis. | Potassium | interferon alpha 1 | Homo sapiens |
| 2 | With a more comprehensive understanding how KS develops and which circumstances provide an increased virulence of this neoplasm in HIV-infected persons, a more subtle rationale for IFN-alpha treatment arose regarding the disorder of the endogenous IFN-system in HIV-positive individuals. | Potassium | interferon alpha 1 | Homo sapiens |
| 3 | With a more comprehensive understanding how KS develops and which circumstances provide an increased virulence of this neoplasm in HIV-infected persons, a more subtle rationale for IFN-alpha treatment arose regarding the disorder of the endogenous IFN-system in HIV-positive individuals. | Potassium | interferon alpha 1 | Homo sapiens |
| 4 | The consequences for treatment options with IFN are a combination with ribavirin in CHC and a graduated systemic treatment schedule in AIDS-KS starting with IFN-treatment in early disease followed by chemotherapy in advanced stages of KS. | Potassium | interferon alpha 1 | Homo sapiens |